Caplamin en es it fr

Caplamin Brand names, Caplamin Analogs

Caplamin Brand Names Mixture

  • No information avaliable

Caplamin Chemical_Formula


Caplamin RX_link

Caplamin fda sheet

Caplamin FDA

Caplamin msds (material safety sheet)

Caplamin MSDS

Caplamin Synthesis Reference

No information avaliable

Caplamin Molecular Weight

131.173 g/mol

Caplamin Melting Point

205 oC

Caplamin H2O Solubility

5.05E+005 mg/L

Caplamin State


Caplamin LogP


Caplamin Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Caplamin Indication

For use in the treatment of excessive postoperative bleeding.

Caplamin Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Caplamin Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Caplamin side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Caplamin Patient Information

Caplamin Organisms Affected

Humans and other mammals