Aminocaproic Acid In Plastic Container
Brand names,
Aminocaproic Acid In Plastic Container
Analogs
Aminocaproic Acid In Plastic Container
Brand Names Mixture
Aminocaproic Acid In Plastic Container
Chemical_Formula
C6H13NO2
Aminocaproic Acid In Plastic Container
RX_link
http://www.rxlist.com/cgi/generic/amicarpre.htm
Aminocaproic Acid In Plastic Container
fda sheet
Aminocaproic Acid In Plastic Container
msds (material safety sheet)
Aminocaproic Acid In Plastic Container
Synthesis Reference
No information avaliable
Aminocaproic Acid In Plastic Container
Molecular Weight
131.173 g/mol
Aminocaproic Acid In Plastic Container
Melting Point
205 oC
Aminocaproic Acid In Plastic Container
H2O Solubility
5.05E+005 mg/L
Aminocaproic Acid In Plastic Container
State
Solid
Aminocaproic Acid In Plastic Container
LogP
0.306
Aminocaproic Acid In Plastic Container
Dosage Forms
Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)
Aminocaproic Acid In Plastic Container
Indication
For use in the treatment of excessive postoperative bleeding.
Aminocaproic Acid In Plastic Container
Pharmacology
Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.
Aminocaproic Acid In Plastic Container
Absorption
Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).
Aminocaproic Acid In Plastic Container
side effects and Toxicity
A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.
Aminocaproic Acid In Plastic Container
Patient Information
Aminocaproic Acid In Plastic Container
Organisms Affected
Humans and other mammals