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Amikar Brand names, Amikar Analogs

Amikar Brand Names Mixture

  • No information avaliable

Amikar Chemical_Formula


Amikar RX_link

Amikar fda sheet

Amikar FDA

Amikar msds (material safety sheet)

Amikar MSDS

Amikar Synthesis Reference

No information avaliable

Amikar Molecular Weight

131.173 g/mol

Amikar Melting Point

205 oC

Amikar H2O Solubility

5.05E+005 mg/L

Amikar State


Amikar LogP


Amikar Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Amikar Indication

For use in the treatment of excessive postoperative bleeding.

Amikar Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Amikar Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Amikar side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Amikar Patient Information

Amikar Organisms Affected

Humans and other mammals