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Hepin Brand names, Hepin Analogs

Hepin Brand Names Mixture

  • No information avaliable

Hepin Chemical_Formula


Hepin RX_link


Hepin fda sheet

Hepin FDA

Hepin msds (material safety sheet)

Hepin MSDS

Hepin Synthesis Reference

No information avaliable

Hepin Molecular Weight

131.173 g/mol

Hepin Melting Point

205 oC

Hepin H2O Solubility

5.05E+005 mg/L

Hepin State


Hepin LogP


Hepin Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Hepin Indication

For use in the treatment of excessive postoperative bleeding.

Hepin Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Hepin Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Hepin side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Hepin Patient Information

Hepin Organisms Affected

Humans and other mammals