Aminocaproic en es it fr

Aminocaproic Brand names, Aminocaproic Analogs

Aminocaproic Brand Names Mixture

  • No information avaliable

Aminocaproic Chemical_Formula


Aminocaproic RX_link

Aminocaproic fda sheet

Aminocaproic FDA

Aminocaproic msds (material safety sheet)

Aminocaproic MSDS

Aminocaproic Synthesis Reference

No information avaliable

Aminocaproic Molecular Weight

131.173 g/mol

Aminocaproic Melting Point

205 oC

Aminocaproic H2O Solubility

5.05E+005 mg/L

Aminocaproic State


Aminocaproic LogP


Aminocaproic Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Aminocaproic Indication

For use in the treatment of excessive postoperative bleeding.

Aminocaproic Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Aminocaproic Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Aminocaproic side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Aminocaproic Patient Information

Aminocaproic Organisms Affected

Humans and other mammals