Proclorperazine
Proclorperazine Brand names, Proclorperazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Proclorperazine Brand Names Mixture
- No information avaliable
Proclorperazine Chemical_Formula
C20H24ClN3S
Proclorperazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Proclorperazine fda sheet
Proclorperazine msds (material safety sheet)
Proclorperazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Proclorperazine Molecular Weight
373.943 g/mol
Proclorperazine Melting Point
228oC
Proclorperazine H2O Solubility
Very slightly soluble
Proclorperazine State
Solid
Proclorperazine LogP
4.99
Proclorperazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Proclorperazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Proclorperazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Proclorperazine Absorption
Rapidly absorbed following oral administration
Proclorperazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Proclorperazine Patient Information
Proclorperazine Organisms Affected
Humans and other mammals
