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Capazine Brand names, Capazine Analogs

Capazine Brand Names Mixture

  • No information avaliable

Capazine Chemical_Formula

C20H24ClN3S

Capazine RX_link

http://www.rxlist.com/cgi/generic/prochlr.htm

Capazine fda sheet

Capazine FDA

Capazine msds (material safety sheet)

Capazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Capazine Molecular Weight

373.943 g/mol

Capazine Melting Point

228oC

Capazine H2O Solubility

Very slightly soluble

Capazine State

Solid

Capazine LogP

4.99

Capazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Capazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Capazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Capazine Absorption

Rapidly absorbed following oral administration

Capazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Capazine Patient Information

Capazine Organisms Affected

Humans and other mammals