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Prochloroperazine Brand names, Prochloroperazine Analogs

Prochloroperazine Brand Names Mixture

  • No information avaliable

Prochloroperazine Chemical_Formula

C20H24ClN3S

Prochloroperazine RX_link

http://www.rxlist.com/cgi/generic/prochlr.htm

Prochloroperazine fda sheet

Prochloroperazine FDA

Prochloroperazine msds (material safety sheet)

Prochloroperazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Prochloroperazine Molecular Weight

373.943 g/mol

Prochloroperazine Melting Point

228oC

Prochloroperazine H2O Solubility

Very slightly soluble

Prochloroperazine State

Solid

Prochloroperazine LogP

4.99

Prochloroperazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Prochloroperazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Prochloroperazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Prochloroperazine Absorption

Rapidly absorbed following oral administration

Prochloroperazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Prochloroperazine Patient Information

Prochloroperazine Organisms Affected

Humans and other mammals