Prochloroperazine
Prochloroperazine Brand names, Prochloroperazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Prochloroperazine Brand Names Mixture
- No information avaliable
Prochloroperazine Chemical_Formula
C20H24ClN3S
Prochloroperazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Prochloroperazine fda sheet
Prochloroperazine msds (material safety sheet)
Prochloroperazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Prochloroperazine Molecular Weight
373.943 g/mol
Prochloroperazine Melting Point
228oC
Prochloroperazine H2O Solubility
Very slightly soluble
Prochloroperazine State
Solid
Prochloroperazine LogP
4.99
Prochloroperazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Prochloroperazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Prochloroperazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Prochloroperazine Absorption
Rapidly absorbed following oral administration
Prochloroperazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Prochloroperazine Patient Information
Prochloroperazine Organisms Affected
Humans and other mammals
