Chlorperazine
Chlorperazine Brand names, Chlorperazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Chlorperazine Brand Names Mixture
- No information avaliable
Chlorperazine Chemical_Formula
C20H24ClN3S
Chlorperazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Chlorperazine fda sheet
Chlorperazine msds (material safety sheet)
Chlorperazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Chlorperazine Molecular Weight
373.943 g/mol
Chlorperazine Melting Point
228oC
Chlorperazine H2O Solubility
Very slightly soluble
Chlorperazine State
Solid
Chlorperazine LogP
4.99
Chlorperazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Chlorperazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Chlorperazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Chlorperazine Absorption
Rapidly absorbed following oral administration
Chlorperazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Chlorperazine Patient Information
Chlorperazine Organisms Affected
Humans and other mammals
