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Chlorperazine Brand names, Chlorperazine Analogs

Chlorperazine Brand Names Mixture

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Chlorperazine Chemical_Formula


Chlorperazine RX_link

Chlorperazine fda sheet

Chlorperazine FDA

Chlorperazine msds (material safety sheet)

Chlorperazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Chlorperazine Molecular Weight

373.943 g/mol

Chlorperazine Melting Point


Chlorperazine H2O Solubility

Very slightly soluble

Chlorperazine State


Chlorperazine LogP


Chlorperazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Chlorperazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Chlorperazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Chlorperazine Absorption

Rapidly absorbed following oral administration

Chlorperazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Chlorperazine Patient Information

Chlorperazine Organisms Affected

Humans and other mammals