Novamin
Novamin Brand names, Novamin Analogs
Novamin Brand Names Mixture
- No information avaliable
Novamin Chemical_Formula
C22H43N5O13
Novamin RX_link
http://www.rxlist.com/cgi/generic3/amikacin.htm
Novamin fda sheet
Novamin msds (material safety sheet)
Novamin Synthesis Reference
H. Kawaguchi, T. Naito, Ger. pat. 2,234,315; H. Kawaguchi et al., U.S. pat. 3,781,268 (both 1973 to Bristol-Myers)
Novamin Molecular Weight
585.603 g/mol
Novamin Melting Point
203-204 oC
Novamin H2O Solubility
1.85E+005 mg/L
Novamin State
Solid
Novamin LogP
-9.048
Novamin Dosage Forms
IM infusion; IM injection
Novamin Indication
For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.
Novamin Pharmacology
Amikacin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Novamin Absorption
Rapidly absorbed after intramuscular administration
Novamin side effects and Toxicity
No information avaliable
Novamin Patient Information
Novamin Organisms Affected
Enteric bacteria and other eubacteria
