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Prochlorperazine edisylate Brand names, Prochlorperazine edisylate Analogs

Prochlorperazine edisylate Brand Names Mixture

  • No information avaliable

Prochlorperazine edisylate Chemical_Formula

C20H24ClN3S

Prochlorperazine edisylate RX_link

http://www.rxlist.com/cgi/generic/prochlr.htm

Prochlorperazine edisylate fda sheet

Prochlorperazine_edisylate FDA

Prochlorperazine edisylate msds (material safety sheet)

Prochlorperazine edisylate Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Prochlorperazine edisylate Molecular Weight

373.943 g/mol

Prochlorperazine edisylate Melting Point

228oC

Prochlorperazine edisylate H2O Solubility

Very slightly soluble

Prochlorperazine edisylate State

Solid

Prochlorperazine edisylate LogP

4.99

Prochlorperazine edisylate Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Prochlorperazine edisylate Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Prochlorperazine edisylate Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Prochlorperazine edisylate Absorption

Rapidly absorbed following oral administration

Prochlorperazine edisylate side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Prochlorperazine edisylate Patient Information

Prochlorperazine edisylate Organisms Affected

Humans and other mammals