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Procloperazine Brand names, Procloperazine Analogs

Procloperazine Brand Names Mixture

  • No information avaliable

Procloperazine Chemical_Formula


Procloperazine RX_link

Procloperazine fda sheet

Procloperazine FDA

Procloperazine msds (material safety sheet)

Procloperazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Procloperazine Molecular Weight

373.943 g/mol

Procloperazine Melting Point


Procloperazine H2O Solubility

Very slightly soluble

Procloperazine State


Procloperazine LogP


Procloperazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Procloperazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Procloperazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Procloperazine Absorption

Rapidly absorbed following oral administration

Procloperazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Procloperazine Patient Information

Procloperazine Organisms Affected

Humans and other mammals