Procloperazine
Procloperazine Brand names, Procloperazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Procloperazine Brand Names Mixture
- No information avaliable
Procloperazine Chemical_Formula
C20H24ClN3S
Procloperazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Procloperazine fda sheet
Procloperazine msds (material safety sheet)
Procloperazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Procloperazine Molecular Weight
373.943 g/mol
Procloperazine Melting Point
228oC
Procloperazine H2O Solubility
Very slightly soluble
Procloperazine State
Solid
Procloperazine LogP
4.99
Procloperazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Procloperazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Procloperazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Procloperazine Absorption
Rapidly absorbed following oral administration
Procloperazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Procloperazine Patient Information
Procloperazine Organisms Affected
Humans and other mammals
