Combid
Combid Brand names, Combid Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Combid Brand Names Mixture
- No information avaliable
Combid Chemical_Formula
C20H24ClN3S
Combid RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Combid fda sheet
Combid msds (material safety sheet)
Combid Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Combid Molecular Weight
373.943 g/mol
Combid Melting Point
228oC
Combid H2O Solubility
Very slightly soluble
Combid State
Solid
Combid LogP
4.99
Combid Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Combid Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Combid Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Combid Absorption
Rapidly absorbed following oral administration
Combid side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Combid Patient Information
Combid Organisms Affected
Humans and other mammals
