Pasotomin
Brand names,
Pasotomin
Analogs
Pasotomin
Brand Names Mixture
Pasotomin
Chemical_Formula
C20H24ClN3S
Pasotomin
RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Pasotomin
fda sheet
Pasotomin
msds (material safety sheet)
Pasotomin
Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Pasotomin
Molecular Weight
373.943 g/mol
Pasotomin
Melting Point
228oC
Pasotomin
H2O Solubility
Very slightly soluble
Pasotomin
State
Solid
Pasotomin
LogP
4.99
Pasotomin
Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Pasotomin
Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Pasotomin
Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Pasotomin
Absorption
Rapidly absorbed following oral administration
Pasotomin
side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Pasotomin
Patient Information
Pasotomin
Organisms Affected
Humans and other mammals