Prochlorperazin
Prochlorperazin Brand names, Prochlorperazin Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Prochlorperazin Brand Names Mixture
- No information avaliable
Prochlorperazin Chemical_Formula
C20H24ClN3S
Prochlorperazin RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Prochlorperazin fda sheet
Prochlorperazin msds (material safety sheet)
Prochlorperazin Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Prochlorperazin Molecular Weight
373.943 g/mol
Prochlorperazin Melting Point
228oC
Prochlorperazin H2O Solubility
Very slightly soluble
Prochlorperazin State
Solid
Prochlorperazin LogP
4.99
Prochlorperazin Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Prochlorperazin Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Prochlorperazin Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Prochlorperazin Absorption
Rapidly absorbed following oral administration
Prochlorperazin side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Prochlorperazin Patient Information
Prochlorperazin Organisms Affected
Humans and other mammals
