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Prochlorpemazine Brand names, Prochlorpemazine Analogs

Prochlorpemazine Brand Names Mixture

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Prochlorpemazine Chemical_Formula


Prochlorpemazine RX_link

Prochlorpemazine fda sheet

Prochlorpemazine FDA

Prochlorpemazine msds (material safety sheet)

Prochlorpemazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Prochlorpemazine Molecular Weight

373.943 g/mol

Prochlorpemazine Melting Point


Prochlorpemazine H2O Solubility

Very slightly soluble

Prochlorpemazine State


Prochlorpemazine LogP


Prochlorpemazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Prochlorpemazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Prochlorpemazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Prochlorpemazine Absorption

Rapidly absorbed following oral administration

Prochlorpemazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Prochlorpemazine Patient Information

Prochlorpemazine Organisms Affected

Humans and other mammals