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Prochlorperazine Brand names, Prochlorperazine Analogs

Prochlorperazine Brand Names Mixture

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Prochlorperazine Chemical_Formula


Prochlorperazine RX_link

Prochlorperazine fda sheet

Prochlorperazine FDA

Prochlorperazine msds (material safety sheet)

Prochlorperazine Synthesis Reference

R. J. Horclois, U.S. Pat. 2,902,484 (1959)

Prochlorperazine Molecular Weight

373.943 g/mol

Prochlorperazine Melting Point


Prochlorperazine H2O Solubility

Very slightly soluble

Prochlorperazine State


Prochlorperazine LogP


Prochlorperazine Dosage Forms

Tablet; Spansule; Capsule; Vial; Suppository; Syrup

Prochlorperazine Indication

For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.

Prochlorperazine Pharmacology

Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.

Prochlorperazine Absorption

Rapidly absorbed following oral administration

Prochlorperazine side effects and Toxicity

Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)

Prochlorperazine Patient Information

Prochlorperazine Organisms Affected

Humans and other mammals