Prochlorperazine
Prochlorperazine Brand names, Prochlorperazine Analogs
- Bayer A 173
- Buccastem
- Compazine
- Capazine
- Chlormeprazine
- Chlorperazine
- Combid
- Compro
- Emelent
- Emetiral
- Eskatrol
- Kronocin
- Meterazin
- Meterazin Maleate
- Meterazine
- Nipodal
- Novamin
- Pasotomin
- Prochloroperazine
- Prochlorpemazine
- Prochlorperazin
- Prochlorperazine edisylate
- Prochlorperazine maleate
- Prochlorpromazine
- Procloperazine
- Proclorperazine
- Stemetil
- Tementil
- Temetid
- Vertigon
Prochlorperazine Brand Names Mixture
- No information avaliable
Prochlorperazine Chemical_Formula
C20H24ClN3S
Prochlorperazine RX_link
http://www.rxlist.com/cgi/generic/prochlr.htm
Prochlorperazine fda sheet
Prochlorperazine msds (material safety sheet)
Prochlorperazine Synthesis Reference
R. J. Horclois, U.S. Pat. 2,902,484 (1959)
Prochlorperazine Molecular Weight
373.943 g/mol
Prochlorperazine Melting Point
228oC
Prochlorperazine H2O Solubility
Very slightly soluble
Prochlorperazine State
Solid
Prochlorperazine LogP
4.99
Prochlorperazine Dosage Forms
Tablet; Spansule; Capsule; Vial; Suppository; Syrup
Prochlorperazine Indication
For control of severe nausea and vomiting, also used in management of the manifestations of psychotic disorders.
Prochlorperazine Pharmacology
Prochlorperazine is a piperazine phenothiazine related to high-potency neuroleptics such as perphenazine. It shares many of the actions and adverse effects of the antipsychotics.
Prochlorperazine Absorption
Rapidly absorbed following oral administration
Prochlorperazine side effects and Toxicity
Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD50=400mg/kg (orally in mice)
Prochlorperazine Patient Information
Prochlorperazine Organisms Affected
Humans and other mammals
