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Grisofulvin Brand names, Grisofulvin Analogs

Grisofulvin Brand Names Mixture

  • No information avaliable

Grisofulvin Chemical_Formula


Grisofulvin RX_link

Grisofulvin fda sheet

Grisofulvin msds (material safety sheet)

Grisofulvin MSDS

Grisofulvin Synthesis Reference

No information avaliable

Grisofulvin Molecular Weight

352.766 g/mol

Grisofulvin Melting Point

220 oC

Grisofulvin H2O Solubility

8.64 mg/L

Grisofulvin State


Grisofulvin LogP


Grisofulvin Dosage Forms

Powder; Tablet

Grisofulvin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grisofulvin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grisofulvin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grisofulvin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grisofulvin Patient Information

Grisofulvin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi