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Grifulin Brand names, Grifulin Analogs

Grifulin Brand Names Mixture

  • No information avaliable

Grifulin Chemical_Formula


Grifulin RX_link

Grifulin fda sheet

Grifulin msds (material safety sheet)

Grifulin MSDS

Grifulin Synthesis Reference

No information avaliable

Grifulin Molecular Weight

352.766 g/mol

Grifulin Melting Point

220 oC

Grifulin H2O Solubility

8.64 mg/L

Grifulin State


Grifulin LogP


Grifulin Dosage Forms

Powder; Tablet

Grifulin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grifulin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grifulin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grifulin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grifulin Patient Information

Grifulin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi