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Likuden Brand names, Likuden Analogs

Likuden Brand Names Mixture

  • No information avaliable

Likuden Chemical_Formula

C17H17ClO6

Likuden RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Likuden fda sheet

Likuden msds (material safety sheet)

Likuden MSDS

Likuden Synthesis Reference

No information avaliable

Likuden Molecular Weight

352.766 g/mol

Likuden Melting Point

220 oC

Likuden H2O Solubility

8.64 mg/L

Likuden State

Solid

Likuden LogP

2.15

Likuden Dosage Forms

Powder; Tablet

Likuden Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Likuden Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Likuden Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Likuden side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Likuden Patient Information

Likuden Organisms Affected

Yeast and other Trichophyton or Microsporum fungi