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Greosin Brand names, Greosin Analogs

Greosin Brand Names Mixture

  • No information avaliable

Greosin Chemical_Formula

C17H17ClO6

Greosin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Greosin fda sheet

Greosin msds (material safety sheet)

Greosin MSDS

Greosin Synthesis Reference

No information avaliable

Greosin Molecular Weight

352.766 g/mol

Greosin Melting Point

220 oC

Greosin H2O Solubility

8.64 mg/L

Greosin State

Solid

Greosin LogP

2.15

Greosin Dosage Forms

Powder; Tablet

Greosin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Greosin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Greosin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Greosin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Greosin Patient Information

Greosin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi