Grizeofulvin en es it fr

Grizeofulvin Brand names, Grizeofulvin Analogs

Grizeofulvin Brand Names Mixture

  • No information avaliable

Grizeofulvin Chemical_Formula


Grizeofulvin RX_link

Grizeofulvin fda sheet

Grizeofulvin msds (material safety sheet)

Grizeofulvin MSDS

Grizeofulvin Synthesis Reference

No information avaliable

Grizeofulvin Molecular Weight

352.766 g/mol

Grizeofulvin Melting Point

220 oC

Grizeofulvin H2O Solubility

8.64 mg/L

Grizeofulvin State


Grizeofulvin LogP


Grizeofulvin Dosage Forms

Powder; Tablet

Grizeofulvin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grizeofulvin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grizeofulvin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grizeofulvin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grizeofulvin Patient Information

Grizeofulvin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi