Grifulvin
Grifulvin Brand names, Grifulvin Analogs
- Amudane
- Biogrisin-fp
- Curling factor
- Delmofulvina
- Fulcin
- Fulcine
- Fulvican grisactin
- Fulvicin
- Fulvicin P/G
- Fulvicin U/F
- Fulvicin-P/G
- Fulvicin-U/F
- Fulvina
- Fulvinil
- Fulvistatin
- Fungivin
- Greosin
- Gresfeed
- Gricin
- Grifulin
- Grifulvin
- Grifulvin V
- Gris-PEG
- Grisactin
- Grisactin Ultra
- Griscofulvin
- Grisefuline
- Griseo
- Griseofulvin [USAN:BAN:INN:JAN]
- Griseofulvin forte
- Griseofulvin-forte
- Griseofulvina [INN-Spanish]
- Griseofulvine [INN-French]
- Griseofulvinum
- Griseofulvinum [INN-Latin]
- Griseomix
- Grisetin
- Grisofulvin
- Grisovin
- Grisovin FP
- Grizeofulvin
- Grysio
- Guservin
- Lamoryl
- Likuden
- Likunden
- Murfulvin
- Neo-Fulcin
- Neocid
- Poncyl
- Spirofulvin
- Sporostatin
- Sporostatin xan
- Xuanjing
Grifulvin Brand Names Mixture
- No information avaliable
Grifulvin Chemical_Formula
C17H17ClO6
Grifulvin RX_link
http://www.rxlist.com/cgi/generic3/griseofulvin.htm
Grifulvin fda sheet
Grifulvin msds (material safety sheet)
Grifulvin Synthesis Reference
No information avaliable
Grifulvin Molecular Weight
352.766 g/mol
Grifulvin Melting Point
220 oC
Grifulvin H2O Solubility
8.64 mg/L
Grifulvin State
Solid
Grifulvin LogP
2.15
Grifulvin Dosage Forms
Powder; Tablet
Grifulvin Indication
For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.
Grifulvin Pharmacology
Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.
Grifulvin Absorption
Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.
Grifulvin side effects and Toxicity
Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions
Grifulvin Patient Information
Grifulvin Organisms Affected
Yeast and other Trichophyton or Microsporum fungi
