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Griscofulvin Brand names, Griscofulvin Analogs

Griscofulvin Brand Names Mixture

  • No information avaliable

Griscofulvin Chemical_Formula


Griscofulvin RX_link

Griscofulvin fda sheet

Griscofulvin msds (material safety sheet)

Griscofulvin MSDS

Griscofulvin Synthesis Reference

No information avaliable

Griscofulvin Molecular Weight

352.766 g/mol

Griscofulvin Melting Point

220 oC

Griscofulvin H2O Solubility

8.64 mg/L

Griscofulvin State


Griscofulvin LogP


Griscofulvin Dosage Forms

Powder; Tablet

Griscofulvin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Griscofulvin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Griscofulvin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Griscofulvin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Griscofulvin Patient Information

Griscofulvin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi