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Fulvicin Brand names, Fulvicin Analogs

Fulvicin Brand Names Mixture

  • No information avaliable

Fulvicin Chemical_Formula

C17H17ClO6

Fulvicin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Fulvicin fda sheet

Fulvicin msds (material safety sheet)

Fulvicin MSDS

Fulvicin Synthesis Reference

No information avaliable

Fulvicin Molecular Weight

352.766 g/mol

Fulvicin Melting Point

220 oC

Fulvicin H2O Solubility

8.64 mg/L

Fulvicin State

Solid

Fulvicin LogP

2.15

Fulvicin Dosage Forms

Powder; Tablet

Fulvicin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Fulvicin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Fulvicin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Fulvicin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Fulvicin Patient Information

Fulvicin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi