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Grisovin Brand names, Grisovin Analogs

Grisovin Brand Names Mixture

  • No information avaliable

Grisovin Chemical_Formula


Grisovin RX_link

Grisovin fda sheet

Grisovin msds (material safety sheet)

Grisovin MSDS

Grisovin Synthesis Reference

No information avaliable

Grisovin Molecular Weight

352.766 g/mol

Grisovin Melting Point

220 oC

Grisovin H2O Solubility

8.64 mg/L

Grisovin State


Grisovin LogP


Grisovin Dosage Forms

Powder; Tablet

Grisovin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grisovin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grisovin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grisovin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grisovin Patient Information

Grisovin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi