Griseofulvinum [INN-Latin] en es it fr

Griseofulvinum [INN-Latin] Brand names, Griseofulvinum [INN-Latin] Analogs

Griseofulvinum [INN-Latin] Brand Names Mixture

  • No information avaliable

Griseofulvinum [INN-Latin] Chemical_Formula


Griseofulvinum [INN-Latin] RX_link

Griseofulvinum [INN-Latin] fda sheet

Griseofulvinum [INN-Latin] msds (material safety sheet)

Griseofulvinum_[INN-Latin] MSDS

Griseofulvinum [INN-Latin] Synthesis Reference

No information avaliable

Griseofulvinum [INN-Latin] Molecular Weight

352.766 g/mol

Griseofulvinum [INN-Latin] Melting Point

220 oC

Griseofulvinum [INN-Latin] H2O Solubility

8.64 mg/L

Griseofulvinum [INN-Latin] State


Griseofulvinum [INN-Latin] LogP


Griseofulvinum [INN-Latin] Dosage Forms

Powder; Tablet

Griseofulvinum [INN-Latin] Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Griseofulvinum [INN-Latin] Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Griseofulvinum [INN-Latin] Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Griseofulvinum [INN-Latin] side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Griseofulvinum [INN-Latin] Patient Information

Griseofulvinum [INN-Latin] Organisms Affected

Yeast and other Trichophyton or Microsporum fungi