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Poncyl Brand names, Poncyl Analogs

Poncyl Brand Names Mixture

  • No information avaliable

Poncyl Chemical_Formula

C17H17ClO6

Poncyl RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Poncyl fda sheet

Poncyl msds (material safety sheet)

Poncyl MSDS

Poncyl Synthesis Reference

No information avaliable

Poncyl Molecular Weight

352.766 g/mol

Poncyl Melting Point

220 oC

Poncyl H2O Solubility

8.64 mg/L

Poncyl State

Solid

Poncyl LogP

2.15

Poncyl Dosage Forms

Powder; Tablet

Poncyl Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Poncyl Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Poncyl Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Poncyl side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Poncyl Patient Information

Poncyl Organisms Affected

Yeast and other Trichophyton or Microsporum fungi