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Fulvistatin Brand names, Fulvistatin Analogs

Fulvistatin Brand Names Mixture

  • No information avaliable

Fulvistatin Chemical_Formula

C17H17ClO6

Fulvistatin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Fulvistatin fda sheet

Fulvistatin msds (material safety sheet)

Fulvistatin MSDS

Fulvistatin Synthesis Reference

No information avaliable

Fulvistatin Molecular Weight

352.766 g/mol

Fulvistatin Melting Point

220 oC

Fulvistatin H2O Solubility

8.64 mg/L

Fulvistatin State

Solid

Fulvistatin LogP

2.15

Fulvistatin Dosage Forms

Powder; Tablet

Fulvistatin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Fulvistatin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Fulvistatin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Fulvistatin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Fulvistatin Patient Information

Fulvistatin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi