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Griseomix Brand names, Griseomix Analogs

Griseomix Brand Names Mixture

  • No information avaliable

Griseomix Chemical_Formula

C17H17ClO6

Griseomix RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Griseomix fda sheet

Griseomix msds (material safety sheet)

Griseomix MSDS

Griseomix Synthesis Reference

No information avaliable

Griseomix Molecular Weight

352.766 g/mol

Griseomix Melting Point

220 oC

Griseomix H2O Solubility

8.64 mg/L

Griseomix State

Solid

Griseomix LogP

2.15

Griseomix Dosage Forms

Powder; Tablet

Griseomix Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Griseomix Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Griseomix Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Griseomix side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Griseomix Patient Information

Griseomix Organisms Affected

Yeast and other Trichophyton or Microsporum fungi