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Griseo Brand names, Griseo Analogs

Griseo Brand Names Mixture

  • No information avaliable

Griseo Chemical_Formula

C17H17ClO6

Griseo RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Griseo fda sheet

Griseo msds (material safety sheet)

Griseo MSDS

Griseo Synthesis Reference

No information avaliable

Griseo Molecular Weight

352.766 g/mol

Griseo Melting Point

220 oC

Griseo H2O Solubility

8.64 mg/L

Griseo State

Solid

Griseo LogP

2.15

Griseo Dosage Forms

Powder; Tablet

Griseo Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Griseo Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Griseo Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Griseo side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Griseo Patient Information

Griseo Organisms Affected

Yeast and other Trichophyton or Microsporum fungi