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Grisefuline Brand names, Grisefuline Analogs

Grisefuline Brand Names Mixture

  • No information avaliable

Grisefuline Chemical_Formula


Grisefuline RX_link

Grisefuline fda sheet

Grisefuline msds (material safety sheet)

Grisefuline MSDS

Grisefuline Synthesis Reference

No information avaliable

Grisefuline Molecular Weight

352.766 g/mol

Grisefuline Melting Point

220 oC

Grisefuline H2O Solubility

8.64 mg/L

Grisefuline State


Grisefuline LogP


Grisefuline Dosage Forms

Powder; Tablet

Grisefuline Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Grisefuline Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Grisefuline Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Grisefuline side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Grisefuline Patient Information

Grisefuline Organisms Affected

Yeast and other Trichophyton or Microsporum fungi