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Sporostatin Brand names, Sporostatin Analogs

Sporostatin Brand Names Mixture

  • No information avaliable

Sporostatin Chemical_Formula

C17H17ClO6

Sporostatin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Sporostatin fda sheet

Sporostatin msds (material safety sheet)

Sporostatin MSDS

Sporostatin Synthesis Reference

No information avaliable

Sporostatin Molecular Weight

352.766 g/mol

Sporostatin Melting Point

220 oC

Sporostatin H2O Solubility

8.64 mg/L

Sporostatin State

Solid

Sporostatin LogP

2.15

Sporostatin Dosage Forms

Powder; Tablet

Sporostatin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Sporostatin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Sporostatin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Sporostatin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Sporostatin Patient Information

Sporostatin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi