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Delmofulvina Brand names, Delmofulvina Analogs

Delmofulvina Brand Names Mixture

  • No information avaliable

Delmofulvina Chemical_Formula

C17H17ClO6

Delmofulvina RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Delmofulvina fda sheet

Delmofulvina msds (material safety sheet)

Delmofulvina MSDS

Delmofulvina Synthesis Reference

No information avaliable

Delmofulvina Molecular Weight

352.766 g/mol

Delmofulvina Melting Point

220 oC

Delmofulvina H2O Solubility

8.64 mg/L

Delmofulvina State

Solid

Delmofulvina LogP

2.15

Delmofulvina Dosage Forms

Powder; Tablet

Delmofulvina Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Delmofulvina Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Delmofulvina Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Delmofulvina side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Delmofulvina Patient Information

Delmofulvina Organisms Affected

Yeast and other Trichophyton or Microsporum fungi