Griseofulvin en es it fr

Griseofulvin Brand names, Griseofulvin Analogs

Griseofulvin Brand Names Mixture

  • No information avaliable

Griseofulvin Chemical_Formula

C17H17ClO6

Griseofulvin RX_link

http://www.rxlist.com/cgi/generic3/griseofulvin.htm

Griseofulvin fda sheet

Griseofulvin msds (material safety sheet)

Griseofulvin MSDS

Griseofulvin Synthesis Reference

No information avaliable

Griseofulvin Molecular Weight

352.766 g/mol

Griseofulvin Melting Point

220 oC

Griseofulvin H2O Solubility

8.64 mg/L

Griseofulvin State

Solid

Griseofulvin LogP

2.15

Griseofulvin Dosage Forms

Powder; Tablet

Griseofulvin Indication

For the treatment of ringworm infections of the skin, hair, and nails, namely: tinea corporis, tinea pedis, tinea cruris, tinea barbae, cradle cap or other conditions caused by Trichophyton or Microsporum fungi.

Griseofulvin Pharmacology

Griseofulvin is a mycotoxic metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years. Griseofulvin is fungistatic with in vitro activity against various species of Microsporum Epidermophyton, and Trichophyton. It has no effect on bacteria or on other genera of fungi. Following oral administration, griseofulvin is deposited in the keratin precursor cells and has a greater affinity for diseased tissue. The drug is tightly bound to the new keratin which becomes highly resistant to fungal invasions.

Griseofulvin Absorption

Poorly absorbed from GI ranging from 25 to 70% of an oral dose. Absorption is significantly enhanced by administration with or after a fatty meal.

Griseofulvin side effects and Toxicity

Side effects are minor: headaches, gastrointestinal reactions and cutaneous eruptions

Griseofulvin Patient Information

Griseofulvin Organisms Affected

Yeast and other Trichophyton or Microsporum fungi