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Fluoroblastin Brand names, Fluoroblastin Analogs

Fluoroblastin Brand Names Mixture

  • No information avaliable

Fluoroblastin Chemical_Formula


Fluoroblastin RX_link


Fluoroblastin fda sheet

Fluoroblastin FDA

Fluoroblastin msds (material safety sheet)

Fluoroblastin MSDS

Fluoroblastin Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluoroblastin Molecular Weight

130.077 g/mol

Fluoroblastin Melting Point


Fluoroblastin H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluoroblastin State


Fluoroblastin LogP


Fluoroblastin Dosage Forms

Topical preparations; Solution for injection

Fluoroblastin Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluoroblastin Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluoroblastin Absorption


Fluoroblastin side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluoroblastin Patient Information

Fluoroblastin Organisms Affected

Humans and other mammals