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Fluri Brand names, Fluri Analogs

Fluri Brand Names Mixture

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Fluri Chemical_Formula


Fluri RX_link


Fluri fda sheet

Fluri FDA

Fluri msds (material safety sheet)

Fluri MSDS

Fluri Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluri Molecular Weight

130.077 g/mol

Fluri Melting Point


Fluri H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluri State


Fluri LogP


Fluri Dosage Forms

Topical preparations; Solution for injection

Fluri Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluri Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluri Absorption


Fluri side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluri Patient Information

Fluri Organisms Affected

Humans and other mammals