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Carzonal Brand names, Carzonal Analogs

Carzonal Brand Names Mixture

  • No information avaliable

Carzonal Chemical_Formula


Carzonal RX_link

Carzonal fda sheet

Carzonal FDA

Carzonal msds (material safety sheet)

Carzonal MSDS

Carzonal Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Carzonal Molecular Weight

130.077 g/mol

Carzonal Melting Point


Carzonal H2O Solubility

< 0.1 g/100 mL at 19 °C

Carzonal State


Carzonal LogP


Carzonal Dosage Forms

Topical preparations; Solution for injection

Carzonal Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Carzonal Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Carzonal Absorption


Carzonal side effects and Toxicity

LD50=230mg/kg (orally in mice)

Carzonal Patient Information

Carzonal Organisms Affected

Humans and other mammals