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Fluro Uracil Brand names, Fluro Uracil Analogs

Fluro Uracil Brand Names Mixture

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Fluro Uracil Chemical_Formula


Fluro Uracil RX_link


Fluro Uracil fda sheet

Fluro_Uracil FDA

Fluro Uracil msds (material safety sheet)

Fluro_Uracil MSDS

Fluro Uracil Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluro Uracil Molecular Weight

130.077 g/mol

Fluro Uracil Melting Point


Fluro Uracil H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluro Uracil State


Fluro Uracil LogP


Fluro Uracil Dosage Forms

Topical preparations; Solution for injection

Fluro Uracil Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluro Uracil Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluro Uracil Absorption


Fluro Uracil side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluro Uracil Patient Information

Fluro Uracil Organisms Affected

Humans and other mammals