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Ftoruracil Brand names, Ftoruracil Analogs

Ftoruracil Brand Names Mixture

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Ftoruracil Chemical_Formula


Ftoruracil RX_link


Ftoruracil fda sheet

Ftoruracil FDA

Ftoruracil msds (material safety sheet)

Ftoruracil MSDS

Ftoruracil Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Ftoruracil Molecular Weight

130.077 g/mol

Ftoruracil Melting Point


Ftoruracil H2O Solubility

< 0.1 g/100 mL at 19 °C

Ftoruracil State


Ftoruracil LogP


Ftoruracil Dosage Forms

Topical preparations; Solution for injection

Ftoruracil Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Ftoruracil Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Ftoruracil Absorption


Ftoruracil side effects and Toxicity

LD50=230mg/kg (orally in mice)

Ftoruracil Patient Information

Ftoruracil Organisms Affected

Humans and other mammals