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Fluoroplex Brand names, Fluoroplex Analogs

Fluoroplex Brand Names Mixture

  • No information avaliable

Fluoroplex Chemical_Formula


Fluoroplex RX_link


Fluoroplex fda sheet

Fluoroplex FDA

Fluoroplex msds (material safety sheet)

Fluoroplex MSDS

Fluoroplex Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluoroplex Molecular Weight

130.077 g/mol

Fluoroplex Melting Point


Fluoroplex H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluoroplex State


Fluoroplex LogP


Fluoroplex Dosage Forms

Topical preparations; Solution for injection

Fluoroplex Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluoroplex Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluoroplex Absorption


Fluoroplex side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluoroplex Patient Information

Fluoroplex Organisms Affected

Humans and other mammals