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Queroplex Brand names, Queroplex Analogs

Queroplex Brand Names Mixture

  • No information avaliable

Queroplex Chemical_Formula


Queroplex RX_link


Queroplex fda sheet

Queroplex FDA

Queroplex msds (material safety sheet)

Queroplex MSDS

Queroplex Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Queroplex Molecular Weight

130.077 g/mol

Queroplex Melting Point


Queroplex H2O Solubility

< 0.1 g/100 mL at 19 °C

Queroplex State


Queroplex LogP


Queroplex Dosage Forms

Topical preparations; Solution for injection

Queroplex Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Queroplex Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Queroplex Absorption


Queroplex side effects and Toxicity

LD50=230mg/kg (orally in mice)

Queroplex Patient Information

Queroplex Organisms Affected

Humans and other mammals