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Fluracil Brand names, Fluracil Analogs

Fluracil Brand Names Mixture

  • No information avaliable

Fluracil Chemical_Formula


Fluracil RX_link


Fluracil fda sheet

Fluracil FDA

Fluracil msds (material safety sheet)

Fluracil MSDS

Fluracil Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluracil Molecular Weight

130.077 g/mol

Fluracil Melting Point


Fluracil H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluracil State


Fluracil LogP


Fluracil Dosage Forms

Topical preparations; Solution for injection

Fluracil Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluracil Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluracil Absorption


Fluracil side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluracil Patient Information

Fluracil Organisms Affected

Humans and other mammals