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Fluril Brand names, Fluril Analogs

Fluril Brand Names Mixture

  • No information avaliable

Fluril Chemical_Formula


Fluril RX_link


Fluril fda sheet

Fluril FDA

Fluril msds (material safety sheet)

Fluril MSDS

Fluril Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Fluril Molecular Weight

130.077 g/mol

Fluril Melting Point


Fluril H2O Solubility

< 0.1 g/100 mL at 19 °C

Fluril State


Fluril LogP


Fluril Dosage Forms

Topical preparations; Solution for injection

Fluril Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Fluril Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Fluril Absorption


Fluril side effects and Toxicity

LD50=230mg/kg (orally in mice)

Fluril Patient Information

Fluril Organisms Affected

Humans and other mammals