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Timazin Brand names, Timazin Analogs

Timazin Brand Names Mixture

  • No information avaliable

Timazin Chemical_Formula


Timazin RX_link


Timazin fda sheet

Timazin FDA

Timazin msds (material safety sheet)

Timazin MSDS

Timazin Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Timazin Molecular Weight

130.077 g/mol

Timazin Melting Point


Timazin H2O Solubility

< 0.1 g/100 mL at 19 °C

Timazin State


Timazin LogP


Timazin Dosage Forms

Topical preparations; Solution for injection

Timazin Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Timazin Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Timazin Absorption


Timazin side effects and Toxicity

LD50=230mg/kg (orally in mice)

Timazin Patient Information

Timazin Organisms Affected

Humans and other mammals