Fenofibrate
Fenofibrate Brand names, Fenofibrate Analogs
- Ankebin
- Antara
- Elasterate
- Elasterin
- FNF
- Fenobrate
- Fenofibrate [Ban:Inn]
- Fenofibrato [Inn-Spanish]
- Fenofibratum [Inn-Latin]
- Fenogal
- Fenotard
- Finofibrate
- Lipanthyl
- Lipantil
- Lipidex
- Lipidil
- Lipidil Micro
- Lipidil Supra
- Lipifen
- Lipirex
- Lipoclar
- Lipofene
- Liposit
- Lipsin
- Lofibra
- Luxacor
- Nolipax
- Procetofen
- Proctofene
- Protolipan
- Secalip
- Sedufen
- Tricor
- Triglide
Fenofibrate Brand Names Mixture
- No information avaliable
Fenofibrate Chemical_Formula
C20H21ClO4
Fenofibrate RX_link
http://www.rxlist.com/cgi/generic3/fenofibrate.htm
Fenofibrate fda sheet
Fenofibrate msds (material safety sheet)
Fenofibrate Synthesis Reference
No information avaliable
Fenofibrate Molecular Weight
360.831 g/mol
Fenofibrate Melting Point
80.5 °C
Fenofibrate H2O Solubility
0.25mg/ml at 25 °C
Fenofibrate State
Solid
Fenofibrate LogP
5.575
Fenofibrate Dosage Forms
Capsule; Tablet
Fenofibrate Indication
For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Fenofibrate Pharmacology
Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.
Fenofibrate Absorption
Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide
Fenofibrate side effects and Toxicity
LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.
Fenofibrate Patient Information
No information avaliable
Fenofibrate Organisms Affected
Humans and other mammals
