Fenofibrate en es it fr

Fenofibrate Brand names, Fenofibrate Analogs

Fenofibrate Brand Names Mixture

  • No information avaliable

Fenofibrate Chemical_Formula

C20H21ClO4

Fenofibrate RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Fenofibrate fda sheet

Fenofibrate FDA

Fenofibrate msds (material safety sheet)

Fenofibrate MSDS

Fenofibrate Synthesis Reference

No information avaliable

Fenofibrate Molecular Weight

360.831 g/mol

Fenofibrate Melting Point

80.5 °C

Fenofibrate H2O Solubility

0.25mg/ml at 25 °C

Fenofibrate State

Solid

Fenofibrate LogP

5.575

Fenofibrate Dosage Forms

Capsule; Tablet

Fenofibrate Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Fenofibrate Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Fenofibrate Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Fenofibrate side effects and Toxicity

LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Fenofibrate Patient Information

No information avaliable

Fenofibrate Organisms Affected

Humans and other mammals