Lipidex

Lipidex Brand names, Lipidex Analogs

Lipidex Brand Names Mixture

No information avaliable

Lipidex Chemical_Formula

C₂₀H₂₁ClO₄

Lipidex RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Lipidex fda sheet

Lipidex FDA

Lipidex msds (material safety sheet)

Lipidex MSDS

Lipidex Synthesis Reference

No information avaliable

Lipidex Molecular Weight

360.831 g/mol

Lipidex Melting Point

80.5 °C

Lipidex H₂O Solubility

0.25mg/ml at 25 °C

Lipidex State

Solid

Lipidex LogP

5.575

Lipidex Dosage Forms

Capsule; Tablet

Lipidex Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Lipidex Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Lipidex Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Lipidex side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Lipidex Patient Information