Lipidil Micro
Brand names,
Lipidil Micro
Analogs
Lipidil Micro
Brand Names Mixture
Lipidil Micro
Chemical_Formula
C20H21ClO4
Lipidil Micro
RX_link
http://www.rxlist.com/cgi/generic3/fenofibrate.htm
Lipidil Micro
fda sheet
Lipidil Micro
msds (material safety sheet)
Lipidil Micro
Synthesis Reference
No information avaliable
Lipidil Micro
Molecular Weight
360.831 g/mol
Lipidil Micro
Melting Point
80.5 °C
Lipidil Micro
H2O Solubility
0.25mg/ml at 25 °C
Lipidil Micro
State
Solid
Lipidil Micro
LogP
5.575
Lipidil Micro
Dosage Forms
Capsule; Tablet
Lipidil Micro
Indication
For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
Lipidil Micro
Pharmacology
Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.
Lipidil Micro
Absorption
Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide
Lipidil Micro
side effects and Toxicity
LD50=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.
Lipidil Micro
Patient Information
No information avaliable
Lipidil Micro
Organisms Affected
Humans and other mammals