FNF

FNF Brand names, FNF Analogs

FNF Brand Names Mixture

No information avaliable

FNF Chemical_Formula

C₂₀H₂₁ClO₄

FNF RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

FNF fda sheet

FNF FDA

FNF msds (material safety sheet)

FNF MSDS

FNF Synthesis Reference

No information avaliable

FNF Molecular Weight

360.831 g/mol

FNF Melting Point

80.5 °C

FNF H₂O Solubility

0.25mg/ml at 25 °C

FNF State

Solid

FNF LogP

5.575

FNF Dosage Forms

Capsule; Tablet

FNF Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

FNF Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

FNF Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

FNF side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

FNF Patient Information