Liposit

Liposit Brand names, Liposit Analogs

Liposit Brand Names Mixture

No information avaliable

Liposit Chemical_Formula

C₂₀H₂₁ClO₄

Liposit RX_link

http://www.rxlist.com/cgi/generic3/fenofibrate.htm

Liposit fda sheet

Liposit FDA

Liposit msds (material safety sheet)

Liposit MSDS

Liposit Synthesis Reference

No information avaliable

Liposit Molecular Weight

360.831 g/mol

Liposit Melting Point

80.5 °C

Liposit H₂O Solubility

0.25mg/ml at 25 °C

Liposit State

Solid

Liposit LogP

5.575

Liposit Dosage Forms

Capsule; Tablet

Liposit Indication

For use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)

Liposit Pharmacology

Fenofibrate is a lipid regulating agent indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb). Fenofibrate is also indicated as adjunctive therapy to diet for treatment of adult patients with hypertriglyceridemia (Fredrickson Types IV and V hyperlipidemia). Fenofibric acid, the active metabolite of Fenofibrate, produces reductions in total cholesterol, LDL cholesterol, apolipoprotein B, total triglycerides and triglyceride rich lipoprotein (VLDL) in treated patients. In addition, treatment with fenofibrate results in increases in high density lipoprotein (HDL) and apoproteins apoAI and apoAII.

Liposit Absorption

Fenofibrate is well absorbed from the gastrointestinal tract. After absorption, fenofibrate is mainly excreted in the urine in the form of metabolites, primarily fenofibric acid and fenofibric acid glucuronide

Liposit side effects and Toxicity

LD₅₀=1600 mg/kg (Oral, in mice); Investigated as a teratogen and reproductive hazard.

Liposit Patient Information